This is a colorimetric competitive immunoassay kit for the quantitative determination of extracellular cGMP. Sensitivity is increased by acetylation (reagents included). Absorbance is read at 405 nm.The ready-to-use liquid color-coded reagents provided reduce error.
Alternative size available: ADI-901-013 (5x96 wells)
Sensitive – optional acetylation protocol increases sensitivity 10-fold (0.088 pmol/ml)
Rapid – reliable results in just 3 hours
Trusted – regularly cited in peer-reviewed publications
Reduce errors – ready-to-use color-coded reagents and pre-coated plates
Simple – efficient and well-established sample handling protocols
Reliable – consistent lot-to-lot performance
环GMP（cGMP）是由鸟苷酸环化酶对GTP的作用形成的，其水平通常比cAMP低10-100倍。一些激素，如乙酰胆碱、胰岛素和催产素，以及某些其他化学物质，如血清素和组胺，会导致cGMP水平升高。鸟苷酸环化酶的刺激剂，如血管扩张剂硝普钠、硝酸甘油、硝酸钠和一氧化氮（NO）也会刺激cGMP水平。
cGMP-ELISA试剂盒是一种用于定量测定细胞外cGMP的比色竞争免疫分析试剂盒。乙酰化可提高灵敏度（包括试剂）。在405 nm处读取吸光度。提供的即用液体色码试剂减少了误差。
cGMP-ELISA试剂盒艾美捷化学参数：
替代名称：循环GMP
灵敏度：（非乙酰化）0.37pmol/ml；（乙酰化）0.088pmol/ml（范围（非乙酰化）0.16-500pmol/ml；（乙酰化）0.16-100 pmol/ml）
化验时间：3小时
应用：ELISA，比色检测
应用说明：用于定量测定任何物种的培养上清液、血浆、血清、唾液和尿液中的cGMP。
波长：405 nm
物种反应性：物种无关
交叉反应性：环状GMP（）和<0.001%：GMP、GTP、环状AMP、AMP、ATP、环状UMP、CTP
使用/稳定性：在+4°C下储存所有成分，-20°C下标准和共轭物除外。
运输：蓝冰运输
内容：GxR IgG微量滴定板、缀合物、抗体、测定缓冲液2、洗涤缓冲液浓缩液、标准品、pNpp底物、停止溶液、乙酸酐、三乙胺
cGMP-ELISA试剂盒——用于细胞外cGMP定量的灵敏（0.088pmol/ml）比色试剂盒。
cGMP-ELISA试剂盒艾美捷特点：
1.敏感–可选乙酰化方案将灵敏度提高10倍（0.088 pmol/ml）
2.仅需3小时即可获得快速可靠的结果
3.可信——定期在同行评审出版物中引用
4.减少错误–即用色码试剂和预涂板
5.简单、高效且成熟的样本处理协议
6.可靠–一致的批量性能
cGMP-ELISA试剂盒文献参考：
Resveratrol treatment may preserve the erectile function after radiotherapy by restoring antioxidant defence mechanisms, SIRT1 and NOS protein expressions: T.E. Sener, et al.; Int. J. Impot. Res. 30, 179 (2018), Application(s): Rat cavernosal tissue lysate, Abstract;
Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control: M.L. Fernandez-Cachon, et al.; Peptides 101, 32 (2017), Abstract;
Sildenafil attenuates hypoxic pulmonary remodelling by inhibiting bone marrow progenitor cells: S. Favre, et al.; J. Cell. Mol. Med. 21, 871 (2017),
