Cetuximab can specifically bind to EGF receptors expressed on the surface of normal cells and a variety of cancer cells, and competitively block EGF and other ligands, such as α Transforming growth factor (TGF- α） A combination of. This product is an IgG1 monoclonal antibody against EGF receptor. After specific combination, it blocks the signal transduction pathway in cells by inhibiting the tyrosine kinase (TK) bound to EGF receptor, thereby inhibiting the proliferation of cancer cells, inducing apoptosis of cancer cells, and reducing the production of matrix metalloproteinases and vascular endothelial growth factor.
Cetuximab is mainly an anti-tumor targeting drug, which is a monoclonal antibody against epidermal growth factor receptor. It can inhibit the vascular growth factor secreted by tumor cells and reduce the neogenesis and metastasis of tumor blood vessels.
When cetuximab is used, there may be hypersensitivity reactions, such as fever, chills, nausea, rash, dyspnea, etc. Therefore, antihistamine drugs must be used before medication.
西妥昔单抗主要是一种抗肿瘤的靶向药物，是针对表皮生长因子受体的单克隆抗体。抑制肿瘤细胞分泌的血管生长因子，减少肿瘤血管的新生和转移。
西妥昔单抗应用时有发生超敏反应的可能，例如发热，寒战，恶心，皮疹，呼吸困难等。因此在用药之前一定要应用抗组胺的药物治疗。
艾美捷西妥昔单抗Cetuximab：
中文名称：西妥昔单抗（抗EGFR）
英文名字：Cetuximab (anti-EGFR)
编号：MBS5759550
规格：1mg /5mg/10mg/25mg/50mg/5x50mg
保存建议：在-20℃下储存3年粉末；-80℃，在溶剂中2年
艾美捷西妥昔单抗Cetuximab相关研究：
抗碳酸酐酶VI（CA6）MBS20003406的多克隆抗体
抗脂肪酸转运蛋白5（FATP5）MBS20003405的生物素连接抗体
淋巴细胞抗原9（LY9）生物素连接抗体MBS20003404
生物素连接的抗消化因子2抗体（GKN2）MBS20003403
抗细胞周期蛋白D1（CCND1）MBS20003402的多克隆抗体
